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Background and AimsNS398, a selective cyclooxygenase‐2 inhibitor, and simvastatin, a 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitor, both exert an anticancer effect on hepatocellular carcinoma cells, but the effect of co‐administration of the two drugs remains unknown. We aimed to investigate the synergistic in vitro anticancer effect of co‐administration of NS398 and simvastatin and its...
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