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A study on the interaction of benzophenanthridine plant alkaloid chelerythrine (CHL) with low pH induced protonated form and conventional B-form DNA was carried out by using a combination of various spectroscopic and viscometric techniques. The interaction of the alkaloid with protonated form of DNA was characterized by the typical hypochromic and bathochromic shifts in the absorption spectrum, increase...
The interaction of two phenazinium dyes namely Phenosafranine (PSF) and Safranin T (ST) with right-handed B-form and left-handed protonated form of Calf Thymus (CT) DNA was investigated using different spectroscopic techniques. Both the dyes have been shown to bind strongly to the right-handed B-form of DNA by the mechanism intercalation as revealed from fluorescence quenching, circular dichroism...
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