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Combined cancer treatment via co‐delivery of siRNAs and an anticancer drug can be a promising strategy due to the synergistic effect of simultaneously minimizing gene/drug administration. In this study, Bcl‐xL siRNA and doxorubicin (DOX) are encapsulated into designed methoxy‐poly(ethylene glycol)‐block‐poly(D,L‐lactic acid) (mPEG‐b‐PLA) block copolymer polymersomes (PSomes). A study of the cytotoxicity...
Front Cover: Bcl‐xL siRNA and DOX encapsulated polymersomes (CPSomes) are synthesized using amphiphilic methoxy‐poly(ethylene glycol)‐block‐poly(lactic acid) copolymers to enhance the stability and delivery efficacy of their contents. Successful delivery of drugs and genes by CPSomes shows its potential as a dual delivery vehicle for cancer treatment. Further details can be found in the article by...
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