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The purpose of this study was to determine the mRNA and protein expression of laminin α chains at various stages of in vitro skin morphogenesis. Fibroblasts in mono-cultures express low levels of the mRNA of laminin α1,α2, α3 and α4 chains. When co-cultured with keratinocytes for 28 days, they expressed the mRNA for all these chains. Keratinocytes in monolayer expressed the laminin α3 chain mRNA and...
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