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Recent studies have shown abnormal expression of CD44s and some of its isoforms in many human malignancies, but little is known about the presence of CD44 in chondrosarcoma. In this study the expression of CD44s and two variant isoforms was evaluated. It was assumed that abnormalities in these receptor proteins may be associated with clinical outcome of the patients.Thirty paraffin-embedded chondrosarcoma...
Das Problem des „cancer of unknown primary (site)“ (CUP) gehört zu den häufigen und vielfach schwierigen Fragestellungen an die diagnostische Histopathologie. Bei der initialen CUP-Situation trägt die relativ kostengünstige und nicht patientenbelastende Immunhistochemie wesentlich zur gezielten Suche und Identifikation des Primärtumors bei. Sie kann in einem zweistufigen Algorithmus durchgeführt werden...
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