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The treatment of cancer-associated pain as well as chronic non-cancer-related pain (CNCP) is an increasingly relevant topic in medicine. However, it has long been recognized that opiates can adversely affect many organ systems, most notably the gastrointestinal system. These are referred to as the spectrum of “opioid-induced bowel dysfunction” (OBD) or what we will refer to as “opioid-induced bowel...
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