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The role of nitric oxide (NO) in multiple sclerosis (MS) is not clear. We found increased cerebrospinal fluid concentrations of the NO degradation products nitrate (NO x ) in clinically definite MS but not in clinically isolated syndromes. High CSF concentrations of NO x correlated with long attack duration. Patients carrying the truncated CC chemokine receptor allele CCR5 Δ32 had...
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