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BACKGROUND
Recent advances in massively parallel sequencing (MPS) technology have provided efficient methods for noninvasive prenatal paternity testing (NIPAT). However, a well‐accepted protocol has not been established. The present study developed an MPS‐based approach for NIPAT and compared the performance of two recently reported methods for MPS data interpretation.
STUDY DESIGN AND METHODS...
BACKGROUND
Researchers have sought to develop a noninvasive protocol for paternity analysis that uses fetal cell‐free DNA (cfDNA) in maternal plasma. Massively parallel sequencing (MPS) is expected to overcome this challenge because it enables the analysis of millions of DNA molecules at a single‐base resolution.
STUDY DESIGN AND METHODS
Seven women were involved in prenatal paternity testing cases...
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