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The monitoring of K+ is very important and emergency because of their unique relationship in various disease diagnosis and treatment. G-quadruplex analogue is a classical recognition unit for K+ detection and has been widely applied in K+ relevant research. Common fluorescent dyes were employed for design of G-quadruplex structure-based K+ probes which suffered from the aggregation-caused quenching...
In this paper, based on reciprocal chiral substrate specificity, taking achiral molecules, ethanolamine (EA) and malachite green (MG) as two model targets, biostable L- DNA aptamers and L-RNA aptamers were generated respectively by chiral inversion of existing D-aptamers. In the detection of EA with L-DNA aptamer-based sensors, the feasibility of our strategy was confirmed, while in the detection...
In this work, with the assistance of the additivity of surface plasmon resonance band of nonionic fluorosurfactant-stabilized gold nanoparticles, we developed a new colorimetric assay approach of cysteine (Cys) and homocysteine (Hcy) in biological fluids, requiring no use of separation techniques. The detection limits of Cys and Hcy can be as low as 0.4μM. The applicability of the method was validated...
A fingerprinting approach was developed by means of gas chromatography–mass spectrometry (GC–MS) and IR spectroscopy for quality control of Portulaca oleracea L., a traditional Chinese food and medicine that has been used for thousands of years in China. Eleven P. oleracea L. samples obtained from different sources were used to establish the fingerprints, and the similarity evaluation and hierarchical...
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