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Summary
Conjunctival melanoma is a rare malignancy, which may give rise to metastases. An effective treatment of these metastases is as yet lacking. Conjunctival melanoma have been found to share specific mutations with cutaneous melanoma, such as mutations in the BRAF genes. As specific treatments have been developed for cutaneous melanoma, one can either try these in patients, or find ways to screen...
Animal models play an important role in understanding tumor growth and studying novel therapies in human cancer research. The significance of results from animal experiments relies on the selection of the proper animal model. Many attempts have been made to create appropriate models for uveal melanoma and its characteristic metastatic route. Ocular models have used Greene melanoma, murine B16 melanoma...
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