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In developing as well as developed countries, diabetes mellitus is one of the major problems. Oxidative stress plays a vital role in generation and maintenance of the diabetic neuropathy. The aim of present investigation was to study the effect of quercetin (10, 20 and 40mg/kg; p.o.) in n-STZ-induced diabetic neuropathy in rats. Streptozotocin (90mg/kg i.p.) was administered to rat pups of age 2days...
Painful peripheral neuropathy induced by chronic ethanol consumption is a major medico-socioeconomical problem. The objective of present investigation was to study the effect of curcumin (20, 40 and 80mg/kg; p.o.) in alcohol-induced neuropathy in rats. Ethanol (35% v/v, 10g/kg; p.o.) was administered for 10 weeks which showed a significant decrease in thermal hyperalgesia, mechanical hyperalgesia,...
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