Search results for: C. Johansen

Items from 1 to 20 out of 71 results

article

HSP90 inhibitor RGRN‐305 for oral treatment of plaque‐type psoriasis: efficacy, safety and biomarker results in an open‐label proof‐of‐concept study*

A. Bregnhøj, K.K.H. Thuesen, T. Emmanuel, T. Litman, more

British Journal of Dermatology > 186 > 5 > 861 - 874

Background HSP90 is a downstream regulator of tumour necrosis factor (TNF)‐α and interleukin (IL)‐17A signalling and may therefore serve as a novel target in the treatment of psoriasis. Objectives This phase Ib proof‐of‐concept study was undertaken to evaluate the safety and efficacy of a novel HSP90 inhibitor (RGRN‐305) in the treatment of plaque psoriasis. Methods We conducted an open‐label,...

article

ANA Podcasts & Webinars: Basilar Artery Stroke

Michelle C. Johansen, Carlo W. Cereda, Jeremy J. Heit

Annals of Neurology > 91 > 4 > 441 - 442

article

ANA Investigates: Tenecteplase

Michelle C. Johansen, Bruce C. V. Campbell

Annals of Neurology > 90 > 1 > 1 - 3

article

Early indicators of primary brain tumours: a population‐based study with 10 years’ follow‐up

M. Marku, B. K. Rasmussen, S. O. Dalton, C. Johansen, more

European Journal of Neurology > 28 > 1 > 278 - 285

Background and purpose To improve diagnoses of primary brain tumours, knowledge about early indicators is needed. Nationwide Danish health registries were used to conduct a population‐based case–control study including all persons diagnosed with a primary brain tumour between 2005 and 2014 in Denmark. Methods All 5135 adults diagnosed with a primary brain tumour in the Danish Cancer Registry were...

article

Embolic Stroke of Unknown Source Clinical Trials and Advances in Research

Michelle C. Johansen, Romergryko G. Geocadin, Hooman Kamel

Annals of Neurology > 88 > 3 > 462 - 463

article

Understanding Atrial Cardiopathy: an Under-Recognized Contributor to Cardioembolic Stroke

Michelle C. Johansen, Henrique Doria Vasconcellos, Rebecca F. Gottesman

Current Treatment Options in Neurology > 2019 > 21 > 7 > 1-16

Purpose of review Ischemic stroke is the fifth leading cause of death in the world with cardioembolic stroke (CES) causing a disproportional amount of the morbidity and mortality associated with stroke. Atrial fibrillation (AF) is the leading cause of CES, and as the population ages, the incidence of CES is anticipated to rise. The importance of proper diagnosis and treatment of patients with embolic-appearing...

article

Quality of life in bladder cancer patients receiving medical oncological treatment; a systematic review of the literature

G. A. Taarnhøj, C. Johansen, H. Pappot

Health and Quality of Life Outcomes > 2019 > 17 > 1 > 1-16

Background Previous quality of life (QoL) literature in bladder cancer (BC) patients has focused on finding the preferred urinary diversion while little is known about the QoL of patients in medical oncological treatment (MOT). We performed a systematic review to assess the existing literature on QoL in patients with muscle-invasive BC (MIBC) undergoing MOT. Methods A systematic search of Pubmed...

article

Commentary on McGillis Hall, L., Lalonde, M., Kashin, J., Yoo, C., & Moran, J. (2017) Changing nurse licensing examinations: media analysis and implication of the Canadian experience

C. Johansen, B. Knowles, D. Jones, P. Dickison

International Nursing Review > 65 > 2 > 159 - 160

article

The effect of an attachment‐oriented couple intervention for breast cancer patients and partners in the early treatment phase: A randomised controlled trial

A. Nicolaisen, M. Hagedoorn, D.G. Hansen, H.L. Flyger, more

Psycho‐Oncology > 27 > 3 > 922 - 928

Objective Patients and partners both cope individually and as a dyad with challenges related to a breast cancer diagnosis. The objective of this study was to evaluate the effect of a psychological attachment‐oriented couple intervention for breast cancer patients and partners in the early treatment phase. Methods A randomised controlled trial including 198 recently diagnosed breast cancer patients...

article

Spatially and temporally resolved regression rate measurements for the combustion of paraffin wax for hybrid rocket motor applications

C. Dunn, G. Gustafson, J. Edwards, T. Dunbrack, more

Aerospace Science and Technology > 2018 > 72 > C > 371-379

Spatially and temporally resolved regression rate measurements were obtained for paraffin wax combustion in a two-dimensional slab-type rocket motor configuration using an optically accessible chamber. The use of high-intensity backlighting and a one-dimensional gray moment edge detection allowed for sub-pixel accuracy for the regression rate of the fuel-grain surface. At higher oxidizer (gaseous...

article

The risk of being depressed is significantly higher in cancer patients than in the general population: Prevalence and severity of depressive symptoms across major cancer types

T.J. Hartung, E. Brähler, H. Faller, M. Härter, more

European Journal of Cancer > 2017 > 72 > C > 46-53

Depression is a common co-morbidity of cancer that has a detrimental effect on quality of life, treatment adherence and potentially survival. We conducted an epidemiological multi-center study including a population-based random comparison sample and estimated the prevalence of depressive symptoms by cancer site, thereby identifying cancer patients with the highest prevalence of depression.We included...

article

Three year follow-up data after RePCa – a randomised rehabilitation study among radiated prostate cancer patients

K.B. Dieperink, C. Johansen, S. Hansen, L. Wagner, more

European Journal of Cancer > 2017 > 72 > S1 > S174

article

TSLP, IL‐31, IL‐33 and sST2 are new biomarkers in endophenotypic profiling of adult and childhood atopic dermatitis

U. Nygaard, M. Hvid, C. Johansen, M. Buchner, more

Journal of the European Academy of Dermatology and Venereology > 30 > 11 > 1930 - 1938

Background Recent years have seen growing interest in identifying new biomarkers in atopic dermatitis (AD) that could serve as indicators of disease severity and predictors of treatment response. Objectives We compared serum levels of thymic stromal lymphopoietin (TSLP), interleukin(IL)‐31, IL‐33 and soluble(s)ST2 in AD patients and healthy controls, investigated the possible correlation with disease...

article

An Evaluation of the Calce Method for Age Estimation

Jessica F. Lam, Alexandra C. Johansen, Tracy L. Rogers

Journal of Forensic Sciences > 61 > 5 > 1319 - 1321

The Calce method of skeletal age estimation (Am J Phys Anthropol, 148, 2012 and 11) uses the acetabular surface of the os coxa and was developed using 90 individuals from the J.C.B. Grant Skeletal collection. From this collection, pilot tests using a combined sample size of 55 randomized individuals yielded an accuracy of 54.5%. To eliminate the possible issue of variation within the collection, 30...

article

Comment on ‘Tumour necrosis factor‐α plays a significant role in the Aldara‐induced skin inflammation in mice’: reply from authors

H. Vinter, L. Iversen, C. Johansen

British Journal of Dermatology > 174 > 6 > 1419 - 1420

article

Tumour necrosis factor‐α plays a significant role in the Aldara‐induced skin inflammation in mice

H. Vinter, K. Kragballe, T. Steiniche, M. Gaestel, more

British Journal of Dermatology > 174 > 5 > 1011 - 1021

BackgroundRecently, the Aldara‐induced psoriasis‐like skin inflammation model in mice has attracted increased attention, due to its dependence on the same immunological pathways and cell types as in human psoriasis. ObjectivesTo study the impact of constitutive deficiency of tumour necrosis factor (TNF)‐α and its upstream regulator mitogen‐activated protein kinase‐activated protein kinase 2 (MAPKAPK‐2,...

article

Diaphragm opening effects on shock wave formation and acceleration in a rectangular cross section channel

S. A. Pakdaman, M. Garcia, E. Teh, D. Lincoln, more

Shock Waves > 2016 > 26 > 6 > 799-813

Shock wave formation and acceleration in a high-aspect ratio cross section shock tube were studied experimentally and numerically. The relative importance of geometric effects and diaphragm opening time on shock formation are assessed. The diaphragm opening time was controlled through the use of slit-type (fast opening time) and petal-type (slow opening time) diaphragms. A novel method of fabricating...

article

Randomised controlled trial of temoporfin photodynamic therapy plus chemotherapy in nonresectable biliary carcinoma—PCS Nordic study

T. Hauge, P.W. Hauge, T. Warloe, A. Drolsum, more

Photodiagnosis and Photodynamic Therapy > 2016 > 13 > C > 330-333

Photodynamic therapy (PDT) in combination with stent have shown promising results in the treatment of biliary tract cancer (BTC) in patients not suitable for surgery. Chemotherapy has been shown to improve survival in patients with local advanced and metastatic BTC.In the current randomized trial the combination of chemotherapy and stent with and without temoporfin (Foscan) photodynamic therapy (PDT),...

chapter

Combustion in a horizontal channel partially filled with porous media

C. Johansen, G. Ciccarelli

Shock Waves > Detonation and Combustion > 209-214

Summary Experiments were carried out to investigate the combustion phenomenon in a horizontal channel partially filled with 12.7 mm diameter ceramic oxide beads. A 1.22 m long, nominally 45 mm thick layer of ceramic oxide beads is located at the ignition end of a 2.44 m long, 76 mm square channel. The channel is filled with a 31 percent nitrogen diluted stoichiometric methane-oxygen mixture and an...

article

The role of leptin in psoriasis comprises a proinflammatory response by the dermal fibroblast

P. Ommen, T. Stjernholm, T. Kragstrup, L. Raaby, more

British Journal of Dermatology > 174 > 1 > 187 - 190

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INFONA - science communication portal

Search results for: C. Johansen

HSP90 inhibitor RGRN‐305 for oral treatment of plaque‐type psoriasis: efficacy, safety and biomarker results in an open‐label proof‐of‐concept study*

ANA Podcasts & Webinars: Basilar Artery Stroke

ANA Investigates: Tenecteplase

Early indicators of primary brain tumours: a population‐based study with 10 years’ follow‐up

Embolic Stroke of Unknown Source Clinical Trials and Advances in Research

Understanding Atrial Cardiopathy: an Under-Recognized Contributor to Cardioembolic Stroke

Quality of life in bladder cancer patients receiving medical oncological treatment; a systematic review of the literature

Commentary on McGillis Hall, L., Lalonde, M., Kashin, J., Yoo, C., & Moran, J. (2017) Changing nurse licensing examinations: media analysis and implication of the Canadian experience

The effect of an attachment‐oriented couple intervention for breast cancer patients and partners in the early treatment phase: A randomised controlled trial

Spatially and temporally resolved regression rate measurements for the combustion of paraffin wax for hybrid rocket motor applications

The risk of being depressed is significantly higher in cancer patients than in the general population: Prevalence and severity of depressive symptoms across major cancer types

Three year follow-up data after RePCa – a randomised rehabilitation study among radiated prostate cancer patients

TSLP, IL‐31, IL‐33 and sST2 are new biomarkers in endophenotypic profiling of adult and childhood atopic dermatitis

An Evaluation of the Calce Method for Age Estimation

Comment on ‘Tumour necrosis factor‐α plays a significant role in the Aldara‐induced skin inflammation in mice’: reply from authors

Tumour necrosis factor‐α plays a significant role in the Aldara‐induced skin inflammation in mice

Diaphragm opening effects on shock wave formation and acceleration in a rectangular cross section channel

Randomised controlled trial of temoporfin photodynamic therapy plus chemotherapy in nonresectable biliary carcinoma—PCS Nordic study

Combustion in a horizontal channel partially filled with porous media

The role of leptin in psoriasis comprises a proinflammatory response by the dermal fibroblast

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