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A number of allocation designs are developed for continuous and binary treatment outcomes to assign a higher number of subjects to the treatment doing better in course of the trial. However, if the response is circular in nature, the definition of a better treatment differs from that under the linear response and hence the already developed designs lack appropriateness. In the current work, redefining...
In the present work we develop a randomized two-treatment adaptive allocation design with covariates ensuring smaller variability of treatment allocations. We study, both numerically and theoretically, several exact and limiting properties of the design and consider an inferential problem following the allocation design. We compare the design with some of the existing allocation designs by computing...
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