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The drugs delivered in the central nervous system can be used for the treatment of Parkinson or Alzheimer by acting directly in the affected zones. The problem is that the Blood Brain Barrier (BBB), only allows the passage of certain substances to protect the brain. The focused ultrasound (FUS) with ultrasonic contrast agents (UCA), have demonstrated the reversible opening of the BBB. This paper presents...
The high-intensity focused ultrasound (HIFU) has shown positive results in the treatment of prostate cancer and its possible application in neurodegenerative diseases. This paper describes the design of a HIFU applicator with a conical geometry, for modeling the software COMSOL® (COMSOL Inc., Burlington, MA) was used, which bases its operation on the finite element method (FEM). The equations that...
Currently the controlled release of drugs in specific areas is of great importance for the treatment of diseases such as cancer, Parkinson, Alzheimer and others. This project works with focused ultrasound (HIFU) in rats, more specifically in the application of HIFU in a specific area of the brain called the substantia nigra, in order to generate opening in the membrane of this area called blood-brain...
At the Nevada Terawatt Facility, experiments are developed to investigate matter in extreme conditions, which is created by the interaction of intense laser-produced plasma with a strong magnetic field. A fast-pulsed-power generator, Zebra, is used to drive coils with megaampere current pulses. Two coil geometries were investigated: two-turn helical coils and horseshoe coils. Finite-element modeling...
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