Search results for: D.A. Scott

Items from 1 to 20 out of 63 results

article

Tobacco‐induced suppression of the vascular response to dental plaque

N. Buduneli, D.A. Scott

Molecular Oral Microbiology > 33 > 4 > 271 - 282

Cigarette smoking presents oral health professionals with a clinical and research conundrum: reduced periodontal vascular responsiveness to the oral biofilm accompanied by increased susceptibility to destructive periodontal diseases. This presents a significant problem, hampering diagnosis and complicating treatment planning. The aim of this review is to summarize contemporary hypotheses that help...

article

Modeling forest site productivity using mapped geospatial attributes within a South Carolina Landscape, USA

B.R. Parresol, D.A. Scott, S.J. Zarnoch, L.A. Edwards, more

Forest Ecology and Management > 2017 > 406 > C > 196-207

Spatially explicit mapping of forest productivity is important to assess many forest management alternatives. We assessed the relationship between mapped variables and site index of forests ranging from southern pine plantations to natural hardwoods on a 74,000-ha landscape in South Carolina, USA. Mapped features used in the analysis were soil association, land use condition in 1951, depth to groundwater,...

article

Big Bang 6Li nucleosynthesis studied deep underground (LUNA collaboration)

D. Trezzi, M. Anders, M. Aliotta, A. Bellini, more

Astroparticle Physics > 2017 > 89 > C > 57-65

The correct prediction of the abundances of the light nuclides produced during the epoch of Big Bang Nucleosynthesis (BBN) is one of the main topics of modern cosmology. For many of the nuclear reactions that are relevant for this epoch, direct experimental cross section data are available, ushering the so-called “age of precision”. The present work addresses an exception to this current status: the...

article

Structure of RagB, a major immunodominant outer‐membrane surface receptor antigen of Porphyromonas gingivalis

T. Goulas, I. Garcia‐Ferrer, J.A. Hutcherson, B.A. Potempa, more

Molecular Oral Microbiology > 31 > 6 > 472 - 485

Porphyromonas gingivalis is the main causative agent of periodontitis. It deregulates the inflammatory and innate host immune responses through virulence factors, which include the immunodominant outer‐membrane surface receptor antigens A (PgRagA) and B (PgRagB), co‐transcribed from the rag pathogenicity island. The former is predicted to be a Ton‐dependent porin‐type translocator but the targets...

article

Man Versus Machine - Is Accurate Automation of Data Abstraction Achievable?

C Kiff, DA Scott, JC Thompson, JM Quigley, more

Value in Health > 2016 > 19 > 7 > A358

article

Considerations in Meta-Analytic Network Design: The Case of Platinum Doublet Chemotherapies in Advanced Non-Small Cell Lung Cancer (Advnsclc)

SM Goring, DA Scott, A Briggs, JR Penrod, more

Value in Health > 2016 > 19 > 7 > A357

article

Adapting Data Sources for Systematic Literature Review Retrieves Additional Data Relevant for Asian HTA

JM O'Rourke, NJ Halfpenny, JM Quigley, DA Scott

Value in Health > 2016 > 19 > 7 > A849

article

Patience is a Virtue When Connecting Evidence Networks

NJ Halfpenny, JM Quigley, B Gurung, DA Scott

Value in Health > 2016 > 19 > 7 > A359

article

Ultra-sensitive γ-ray spectroscopy set-up for investigating primordial lithium problem

G. Gervino, C. Gustavino, D. Trezzi, M. Aliotta, more

Nuclear Instruments and Methods in Physics Research Section A: Accelerators,... > 2016 > 824 > C > 617-619

To precisely determine BBN ⁶Li production, the cross-section of the nuclear reaction ²H(α, γ)⁶Li must be directly measured within the astrophysical energy range of 30–400keV. This measure requires an ultra-low γ-ray background in the experimental set-up. We have realized the conditions matching these very strict requirements at LUNA, the deep underground accelerator laboratory active in the INFN Gran...

article

Comparison of inherently essential genes of Porphyromonas gingivalis identified in two transposon‐sequencing libraries

J.A. Hutcherson, H. Gogeneni, D. Yoder‐Himes, E.L. Hendrickson, more

Molecular Oral Microbiology > 31 > 4 > 354 - 364

Porphyromonas gingivalis is a Gram‐negative anaerobe and keystone periodontal pathogen. A mariner transposon insertion mutant library has recently been used to define 463 genes as putatively essential for the in vitro growth of P. gingivalis ATCC 33277 in planktonic culture (Library 1). We have independently generated a transposon insertion mutant library (Library 2) for the same P. gingivalis strain...

article

QUANTIFYING AND ADJUSTING FOR EFFECT MODIFICATION IN INDIRECT TREATMENT COMPARISONS

S.M. Goring, J.B. Wilson, J.C. Thompson, D.A. Scott

Value in Health > 2016 > 19 > 3 > A90

article

Synthesis Of Time-To-Event Data For Cost-Effectiveness Analysis: Proportional Hazards Or Accelerated Failure Time Scale?

C Parker, A Padhiar, DA Scott

Value in Health > 2016 > 19 > 3 > A99

article

Are Meaningful Discussions About Adherence in Reimbursement Submissions of Chronic Diseases Hindered by Reporting Heterogeneity?

JM Quigley, NJ Halfpenny, KE Ward, JM O’Rourke, more

Value in Health > 2016 > 19 > 3 > A73-A74

article

Spinal cord protection in aortic endovascular surgery

D.A. Scott, M.J. Denton

British Journal of Anaesthesia > 2016 > 117 > S2 > ii26-ii31

A persistent neurological deficit, such as paraplegia or paraparesis, secondary to spinal cord injury remains one of the most feared complications of surgery on the descending thoracic or abdominal aorta. This is despite sophisticated advances in imaging and the use of less invasive endovascular procedures. Extensive fenestrated endovascular aortic graft prostheses still carry a risk of spinal cord...

article

A Conceptual Search Filter to Identify Real-World Evidence

K Ogden, JC Thompson, NJ Halfpenny, DA Scott

Value in Health > 2015 > 18 > 7 > A728

article

Time Ratios Or Hazard Ratios: Accelerating Toward A New Approach?

A Padhiar, C Parker, JM Quigley, S Mealing, more

Value in Health > 2015 > 18 > 7 > A686

article

Critical Appraisal Of Real World Evidence – A Review Of Recommended And Commonly Used Tools

JM Quigley, JC Thompson, NJ Halfpenny, DA Scott

Value in Health > 2015 > 18 > 7 > A684

article

Soil C and N storage and microbial biomass in US southern pine forests: Influence of forest management

J.A. Foote, T.W. Boutton, D.A. Scott

Forest Ecology and Management > 2015 > 355 > C > 48-57

Land management practices have strong potential to modify the biogeochemistry of forest soils, with implications for the long-term sustainability and productivity of forestlands. The Long-Term Soil Productivity (LTSP) program, a network of 62 sites across the USA and Canada, was initiated to address concerns over possible losses of soil productivity due to soil disturbance from forest management....

article

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in adults 18–49 years of age, naive to 23-valent pneumococcal polysaccharide vaccine

K.A. Bryant, R. Frenck, A. Gurtman, J. Rubino, more

Vaccine > 2015 > 33 > 43 > 5854-5860

Based on the success of vaccination with pneumococcal conjugate vaccines (PCVs) in children, recent studies have focused on PCVs in adults. Data from a randomized, double-blind study comparing the immunogenicity, tolerability, and safety of the 13-valent PCV (PCV13) and the 23-valent pneumococcal polysaccharide vaccine (PPSV23) in PPSV23-naive adults 60–64 years of age have been published. The same...

article

Porphyromonas gingivalis RagB is a proinflammatory signal transducer and activator of transcription 4 agonist

J.A. Hutcherson, J. Bagaitkar, K. Nagano, F. Yoshimura, more

Molecular Oral Microbiology > 30 > 3 > 242 - 252

Periodontal diseases are semi‐ubiquitous and caused by chronic, plaque‐induced inflammation. The 55‐kDa immunodominant RagB outer membrane protein of Porphyromonas gingivalis, a keystone periodontal pathogen, has been proposed to facilitate nutrient transport. However, potential interactions between RagB and the innate response have not been examined. We determined that RagB exposure led to the differential...

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Search results for: D.A. Scott

Tobacco‐induced suppression of the vascular response to dental plaque

Modeling forest site productivity using mapped geospatial attributes within a South Carolina Landscape, USA

Big Bang 6Li nucleosynthesis studied deep underground (LUNA collaboration)

Structure of RagB, a major immunodominant outer‐membrane surface receptor antigen of Porphyromonas gingivalis

Man Versus Machine - Is Accurate Automation of Data Abstraction Achievable?

Considerations in Meta-Analytic Network Design: The Case of Platinum Doublet Chemotherapies in Advanced Non-Small Cell Lung Cancer (Advnsclc)

Adapting Data Sources for Systematic Literature Review Retrieves Additional Data Relevant for Asian HTA

Patience is a Virtue When Connecting Evidence Networks

Ultra-sensitive γ-ray spectroscopy set-up for investigating primordial lithium problem

Comparison of inherently essential genes of Porphyromonas gingivalis identified in two transposon‐sequencing libraries

QUANTIFYING AND ADJUSTING FOR EFFECT MODIFICATION IN INDIRECT TREATMENT COMPARISONS

Synthesis Of Time-To-Event Data For Cost-Effectiveness Analysis: Proportional Hazards Or Accelerated Failure Time Scale?

Are Meaningful Discussions About Adherence in Reimbursement Submissions of Chronic Diseases Hindered by Reporting Heterogeneity?

Spinal cord protection in aortic endovascular surgery

A Conceptual Search Filter to Identify Real-World Evidence

Time Ratios Or Hazard Ratios: Accelerating Toward A New Approach?

Critical Appraisal Of Real World Evidence – A Review Of Recommended And Commonly Used Tools

Soil C and N storage and microbial biomass in US southern pine forests: Influence of forest management

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in adults 18–49 years of age, naive to 23-valent pneumococcal polysaccharide vaccine

Porphyromonas gingivalis RagB is a proinflammatory signal transducer and activator of transcription 4 agonist

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