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Experiments were carried out to investigate age- and dose-dependent effects of the selective AT1 receptor antagonist, ZD 7155, and the selective AT2 receptor antagonist, PD 123319, on systemic and renal hemodynamics in conscious, chronically instrumented lambs aged ∼1 and ∼6 weeks of postnatal life. Mean arterial pressure (MAP), mean venous pressure (MVP), and renal blood flow (RBF) were measured...
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