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A central pathological feature of Alzheimer's disease is the profuse deposition of amyloid-β protein (Aβ) in the brain parenchyma and vessel walls. Aβ also forms deposits in the brains of a variety of mammals, including all aged non-human primates studied to date. The sequence of Aβ in these animals is identical to that in humans. No Aβ deposits have been found in the brains of wild-type rats and...
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