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As a possible viable and non‐invasive method to identify high producing cells, Confocal Raman Microscopy was shown to be able to differentiate CHO host cell lines and derivative production clones. Cluster analysis of spectra and their derivatives was able to differentiate between different producer cell lines and a host, and also distinguished between an intracellular region of high lipid and protein...
MicroRNAs (miRNAs) are a novel class of short non‐coding RNAs, which negatively regulate target gene expression at post‐transcriptional level. They mediate an important layer of control in the global regulation of gene networks, controlling a broad range of physiological as well as patho‐physiological pathways including development, cancer, metabolism, proliferation, and stress resistance. So far,...
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