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Tc-99m MDP whole body bone scan using single photon emission computed tomography (SPECT) is an important and general method to investigate the spreading of malignant tumors. However, it is time-consuming for doctors to perform three-dimensional (3D) assessment using SPECT images. Therefore, a computer-aided diagnosis (CAD) system is required to identify suspicious locations of bone abnormalities....
Adjustment of brightness and contrast in nuclear medicine whole body bone scan images may confuse nuclear medicine physicians when identifying small bone lesions as well as making the identification of subtle bone lesion changes in sequential studies difficult. In this study, we developed a computer-aided diagnosis system, based on the fuzzy sets histogram thresholding method and anatomical knowledge-based...
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