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The degradation of poly(trimethylene carbonate) (PTMC) implants with different molecular weights was investigated in vitro and in vivo. The results showed that PTMC degraded in vitro enzymolysis case and in vivo via surface erosion. The effect of the molecular weight on the degradation rate of PTMC was investigated in light of hydrophilicity and form-stability. A higher degradation rate was seen in...
The degradation behavior of P(TMC-co-CL) in different compositions was investigated via subcutaneous implantation in vivo. To clarify the role of enzymes in the degradation behavior of the copolymers, hydrolytic and enzymatic degradation were also performed. The mass loss, changes in molecular weight and polydispersity, as well as the variation in composition were monitored with degradation. The changes...
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