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In article number 2008353, Young Keun Kim, Heemin Kang, and co‐workers report a magnetic nanocoil system that enables remote control of reversible stretching and shrinking of ligand‐presenting nanocoils on a material surface, thereby modulating the ligand pitch in the nanocoils, which controls in situ and time‐regulated focal adhesion, mechanotransduction, and differentiation of stem cells in vivo...
Native extracellular matrix (ECM) can exhibit cyclic nanoscale stretching and shrinking of ligands to regulate complex cell–material interactions. Designing materials that allow cyclic control of changes in intrinsic ligand‐presenting nanostructures in situ can emulate ECM dynamicity to regulate cellular adhesion. Unprecedented remote control of rapid, cyclic, and mechanical stretching (“ON”) and...
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