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Although several interfaces for CE‐MS hyphenation are commercially available, the development of new versatile, simple and yet efficient and sensitive alternatives remains an important field of research. In a previous work, a simple low sheath‐flow interface was developed from inexpensive parts. This interface features a design easy to build, maintain, and adapt to particular needs. The present work...
The current trend for increasing technical complexity in the field of CE‐ESI‐MS interfaces has incited for more accessible alternatives. In this work, a simple low sheath‐flow ESI interface operating in the submicroliter nanospray regime without nebulizing gas assistance was evaluated. The use of sheath liquid enabled improving the ionization of the analytes, while the absence of nebulizing gas minimized...
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