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Trophic interactions between neurons and enwrapping glia, and between neurons and target cells, provide plasticity to the mammalian nervous system. Here, we review evidence that analogous cell interactions operate in the development of the nervous system of the fruit‐fly Drosophila. Homologues of the canonical mammalian trophic factors also maintain neuronal and glial survival in Drosophila, adjusting...
Infection with bovine viral diarrhea virus (BVDV) causes different effects depending on its biotype in vitro; cytopathogenic (cp) strains induce apoptosis, type I interferon (IFN), and various stress-mediated responses, whereas non-cytopathogenic (ncp) strains do not. However, comprehensive transcriptional profiles of the cells infected with BVDV are still unknown. Here we performed microarray analysis...
Persistent infection in cattle with bovine viral diarrhea virus (BVDV), which is classified in the genus Pestivirus, family Flaviviridae, may result in growth retardation and immunosuppression. In vitro infection with noncytopathogenic (ncp) BVDV has been shown to suppress interferon (IFN) responses, whereas ncpBVDV induces transient strong IFN responses in vivo following acute infection of naïve...
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