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Background and aims
Several studies have indicated an association between maternal prenatal substance use and offspring externalizing disorders; however, it is uncertain whether this relationship is causal. We conducted a systematic review to determine: (1) if the literature supports a causal role of maternal prenatal substance use on offspring externalizing disorders diagnosis and (2) whether these...
Background and aims
Studies have indicated that maternal prenatal substance use may be associated with offspring attention deficit hyperactivity disorder (ADHD) via intrauterine effects. We measured associations between prenatal smoking, alcohol and caffeine consumption with childhood ADHD symptoms accounting for shared familial factors.
Design
First, we used a negative control design comparing...
Background and aims
Previous studies suggest an association between maternal tobacco and caffeine consumption during and outside of pregnancy and offspring mental health. We aimed to separate effects of the maternal environment (intrauterine or postnatal) from pleiotropic genetic effects.
Design
Secondary analysis of a longitudinal study. We (i) validated smoking and caffeine genetic risk scores...
Aims
To evaluate the utility of coffee‐related genetic variants as proxies for coffee consumption in Mendelian randomization studies, by examining their association with non‐alcoholic beverage consumption (including subtypes of coffee and tea) and a range of socio‐demographic and life‐style factors.
Design
Observational study of the association of genetic risk scores for coffee consumption with...
AimsTo estimate associations between smoking initiation, smoking persistence and smoking heaviness and caffeine consumption in two population‐based samples from the Netherlands and the United Kingdom.
DesignObservational study employing data on self‐reported smoking behaviour and caffeine consumption.
SettingAdults from the general population in the Netherlands and the United Kingdom.
ParticipantsParticipants...
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