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Despite several therapeutic options renal cell carcinoma is associated with a poor clinical outcome. Therefore, we investigated whether combining 5-fluorouracil with the histone deacetylase inhibitor belinostat would exert a synergistic effect on renal cell carcinoma cells in vitro and in vivo.We used SN12C cells treated with 5-fluorouracil and/or belinostat in vitro and in xenograft experiments in vivo...
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