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To test the clinical value of transthoracic Doppler echocardiography (TTE) for the measurement of intramyocardial coronary blood flow velocity (ICFV) and coronary flow reserve (CFR), TTE was performed in 12 patients (pts) with a critical stenosis (=<75% diameter stenosis) of the left anterior descending coronary artery (LAD) (7-16 years) in Kawasaki disease and 16 pts (3-12 years) with normal LAD...
Background: It has been suggested that mechanical stretch may enhance the L-type Ca 2+ channel current (I Ca ) in atrial cells. This can consistently explain the Frank-Starling mechanism if it also operates in ventricular cells. Thus, we studied the effects of cell swelling on I Ca , intracellular free Ca 2+ ([Ca 2+ ] i ),...
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