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The histone demethylase KDM5B is considered to be a promising target for anticancer therapy. Single‐chain antibodies from llama (nanobodies) have been raised to aid in crystallization and structure determination of this enzyme. The antigen‐binding properties of 15 of these nanobodies have been characterized. The crystal structure of one of these (NB17) has been determined to a resolution of 1.85 Å...
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