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Background and Objective: Interleukin‐8 (IL‐8) is a central chemokine in acute respiratory distress syndrome (ARDS), and the IL‐8 gene contains a functional single nucleotide polymorphism (SNP) −251A/T in its promoter region. We hypothesized that IL‐8 −251A/T SNP is associated with PaO2/FiO2 in critically ill patients.
Methods: We conducted genetic‐association studies in intensive care units at...
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