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Serious infection and the patient’s response (sepsis) is a serious health problem that, even today, is associated with a mortality rate of 30 %–50 %. The phases of severe sepsis include an early hyperinflammatory response to pathogens and a late immunosuppressed phase. Toll-like receptors (TLRs) are a family of transmembrane innate immune receptors that play a major role in both phases of sepsis....
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