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Background/Aims: Bile acids have previously been used as shuttles for directing organic drugs to the liver. The aim of this study was to investigate liver transport and biotransformation of a new cytostatic bioinorganic complex (Bamet-H2), that was obtained by binding platinum(II) to two cholylglycinate moieties.Methods: Using rat hepatocytes in primary culture, the kinetics of cholylglycinate, cisplatin...
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