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β-Lapachone (1) is a natural ortho-naphthoquinone that has been shown to have a variety of pharmacological effects, mainly anticancer activity. As a single agent, β-lapachone has demonstrated significant antineoplastic activity against several human cancer cell lines at concentrations typically in the range of 1–10μM (IC 50 ). The use of cyclodextrins is useful to overcome solubility and bioavailability...
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