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In rats, serum secretory component (SC) iselevated in mechanical but not hepatocellularcholestasis. To determine if serum SC might distinguishcholestatic syndromes in humans, serum samples wereobtained from control subjects and patients withmechanical and hepatocellular cholestasis. Equal volumesof serum were assayed for SC by immunoblotting with anantibody specific for human SC. Quantitativedensitometry...
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