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BACKGROUND:Casitas B‐lineage lymphoma (Cbl) is an E3 ubiquitin ligase of many tyrosine kinase receptors. The authors previously detected c‐Cbl mutation and low protein expression in non‐small cell lung cancer (NSCLC). Therefore, it was hypothesized that overexpression of wild‐type c‐Cbl (c‐Cbl WT) exhibits tumor growth inhibition.
METHODS:Wound healing and transwell assays were conducted to examine...
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