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Japan has experienced a drastic increase in the incidence of prostate cancer (PC). To assess changes in the risk for PC, we investigated baseline prostate specific antigen (PSA) levels in first‐time screened men, across a 25‐year period. In total, 72,654 men, aged 50–79, underwent first‐time PSA screening in Gunma prefecture between 1992 and 2016. Changes in the distribution of PSA levels were investigated,...
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