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A new polyketide metabolite, nodulisporin A was isolated from the fungicolous Nodulisporium sp. SH-1. The structure of compound 1 was elucidated by analyses of NMR spectroscopic and mass spectrometry data in combination with chemical means. Compound 1 is an equilibrium mixture of a linear form and two hemiacetal forms at the C-8 carbon. Compound 1 was evaluated for cytotoxic and antimicrobial activities...
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