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(S)-carbonyl reductase II (SCRII), a short-chain alcohol dehydrogenase from Candida parapsilosis M203011, catalyzes the bioreduction of 2-hydroxyacetophenone (2-HAP) to (S)-1-phenyl-1,2-ethanediol ((S)-PED). When SCRII was expressed in Escherichia coli, the biotransformation efficiency of (S)-PED was low. To improve its biocatalytic efficiency, the homologous expression of SCRII in C. parapsilosis...
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