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We assessed the metabolism of low density lipoprotein (LDL) of human monocyte-derived macrophages under hypoxia. The specific binding and association of 125 I-labeled LDL ( 125 I-LDL) were not changed under hypoxia compared to normoxia. However, the degradation of 125 I-LDL under hypoxia decreased to 60%. The rate of cholesterol esterification...
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