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Disintegrant is a typical excipient that improves the solubility, dissolution and bioavailability of drug. In this study, the application of nanocrystalline cellulose (NCC) as a potential disintegrant in the preparation of tablet was investigated. Angle of repose of NCC was 44.26° which was between L-HPC and MCC suggesting a good fluidity of NCC. Swelling property of NCC was between CMS-Na and MCC...
An arabinoglucan, named APS-1d with a molecular weight of 5.1kDa determined by high-performance gel-permeation chromatography, was extracted from the roots of Angelica sinensis (Oliv.) Diels and further purified by DEAE-Sephadex A-25 and Sephadex G-100 columns. The monosaccharides in the APS-1d, determined by GC, consisted of Glc and Ara in molar ratio of 13.8:1. Using methylation analysis, partial...
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