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Interleukin‐20 (IL‐20) is an IL‐10‐family cytokine that regulates innate and adaptive immunity in skin and other tissues. In addition to protecting the host from various external pathogens, dysregulated IL‐20 signaling has been shown to contribute to the pathogenesis of human psoriasis. IL‐20 signals through two cell‐surface receptor heterodimers, IL‐20R1–IL‐20R2 and IL‐22R1–IL‐20R2. In this report,...
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