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Cytochromes bd are terminal oxidases in the respiratory chains of many prokaryotic organisms. They reduce O 2 to 2H 2 O at the expense of electrons extracted from quinol. The oxidases can be divided into two subfamilies, L and S, based on the presence of either a long or a short hydrophilic connection between transmembrane helices 6 and 7 in subunit I designated as ‘Q-loop’. The L-subfamily...
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