The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Humanity is currently facing various diseases with significant mortality rates, particularly those associated with malignancies. Numerous enzymes and proteins have been identified as highly promising targets for the treatment of cancer. The poly(ADP‐ribose) polymerases (PARPs) family comprises 17 members which are essential in DNA damage repair, allowing the survival of cancer cells. Unlike other...
Using a molecular hybridization approach, a new series of isatin‐quinazoline hybrids 15a–o was designed and synthesized via two different synthetic routes. The target compounds 15a–o were prepared by the reaction of quinazoline hydrazines 12a–e with indoline‐2,3‐diones 13a–c or by treating 4‐chloroquinazoline derivatives 11a–e with isatin hydrazones 14a–c. The in vitro anticancer activity of the newly...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.