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In murine models, challenge with different viral and parasitic infection is closely associated with the production of type I interferons (IFN-α/β) and NK cell production of interferon-γ (IFN-γ). Therefore, we wished to determine if IFN-α/β had a role in the regulation of NK cell production of IFN-γ. IFN-α/β alone stimulated low levels of IFN-γ production by purified populations of IL-2 activated...
A series of covalently-connected azobenzene-porphyrin derivatives have been synthesised and their photochemical properties investigated. The photochemistry of the porphyrin components is essentially unaltered, but photochemical isomerisation of the azobenzene components can not be detected.
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