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The inhibition of four β-glucosidases of plant, fungal, and mammalian origin by N 1 -butyl- andN 1 -dodecyl-D-gluconamidine was determined. Comparison with the inhibition by the correspondingN -alkyl-D-glucosylamines revealed that the strongly basic amidines (pK a 10.8) were at the most 10-times more inhibitory than the weakly basic glucosylamines (pK a 6.5). The small...
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