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The growing resistance of Streptococcus pneumoniae to penicillin can be overcome by increasing the dose of the penicillin administered. This generated the recommendation that the adult dose of amoxicillin for the treatment of acute maxillary sinusitis (AMS) be increased from 1.5g/day to 4.0g/day. The objective of this study was to investigate whether the higher dose of amoxicillin is more effective...
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