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Na + ,K + -ATPase and Ca 2+ -ATPase activities have not been studied quantitatively in the cochlea affected by endolymphatic hydrops. The present study was designed to measure quantitatively the Na + ,K + -ATPase and Ca 2+ -ATPase activities in the cochlear lateral wall and the threshold of auditory brainstem response (ABR) for guinea pigs...
Na + ,K + -ATPase and Ca 2+ -ATPase are well known participants in the active transport of ions in the inner ear. These two enzymes play an important role in maintaining cochlear function. Although changes in these enzymes' activities in the cochlea have been implicated in noise-induced hearing loss, no evidence of quantitative alteration of Na + ,K + -ATPase...
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