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A dual-gate ion-sensitive field-effect transistor (DGFET) with the back-side sensing structure implemented in a 0.18 μm SOI-CMOS SoC platform realizing high performance bioelectrical detection with non-ideal effect reduction is presented. Non-ideal effects of the conventional ISFET, such as time drift and hysteresis, are suppressed by the innovative scheme in DGFET using the bottom poly-gate (PG)...
We demonstrate low-voltage Ge waveguide avalanche photodetectors (APDs) with gain-bandwidth product over 100GHz. A 5.8dB avalanche sensitivity improvement (1×10−12 bit error ratio at 10Gb/s) is obtained for the wire-bonded optical receiver at −5.9V APD bias.
High sensitivity L13-type two-dimensional photonic crystal microcavities with nanoholes were fabricated by 193nm photolithography. 0.03 picomolar concentration pancreatic cancer biomarker in patient serum samples was experimentally detected to 10× lower dilution than ELISA.
We experimentally demonstrate the first holey and slotted photonic crystal waveguides in silicon-on-sapphire at mid-infrared wavelength of 3.43μm. Chemical warfare simulant triethylphosphate was detected in gas phase at 10ppm concentration via optical absorbance signature.
Six orders of magnitude wide dynamic range (0.1ng/ml to over 100μg/ml), label-free detection of gentamicin small molecules with silicon photonic crystal microcavity biosensors multiplexed by multimode interference power splitters was experimentally demonstrated. Detection specificity was confirmed.
We demonstrate low-voltage germanium waveguide avalanche photodetectors (APD) with gain-bandwidth product of 88GHz. A 7.1dB sensitivity improvement is demonstrated for an APD wire-bonded to a 10Gb/s CMOS transimpedance amplifier, at −6.2V APD bias.
We compared different on-chip silicon based absorption sensors for the detection of xylene in water in both near-infrared and mid-infrared with detection limit down to 1ppb. Strip waveguide, slot waveguide and PC-based chip integrated optical absorption spectroscopy devices are compared in near-infrared and mid-infrared. The results provide a route for enhanced sensitivity while retaining device miniaturization.
We demonstrate that coupled cavity-waveguide architectures can lead to enhanced experimentally measured detection limit of 300 fM (20pg/ml) for sensing the binding of avidin to biotin in photonic crystal micro-cavity based biosensor.
We experimentally demonstrate that in photonic crystal sensors with side-coupled cavity-waveguide, group velocity of propagating mode in the coupled waveguide at the resonant mode frequency enhances sensitivity in addition to microcavity mode engineering.
We experimentally demonstrate a photonic crystal microcavity biosensor with 1pM sensitivity. Radiation loss engineering for high Q and increased mode overlap with analyte are combined to achieve the highest sensitivity in silicon-on-insulator platform.
We experimentally detect lung cancer cell lysates with high sensitivity down to 2 cells per microliter with silicon based photonic crystal microcavity sensors. Label free specificity is achieved via sandwiched assays and simultaneous multiplexed detection.
A low-power and high-performance RFCMOS SoC GPS receiver is introduced in this paper. It is fabricated in a 0.11 mum process with 6.2times6.2mmz TFBGA package. The power consumption is 34 mW during tracking stage and 45 mW during acquisition stage. The tracking sensitivity is up to -165 dBm with the most competitive TTFF performance. This GPS receiver is designed for PND/GSM/CDMA handsets and is compatible...
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