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Using conflict drinking and forced swimming tests in rats, we examined the anxiolytic- and the antidepressant-like activity, respectively, of (2R)-1-[(3-hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]-pyrrolidine (SB 269970), a selective 5-HT 7 receptor antagonist, after its intrahippocampal administration. SB 269970 at doses of 0.3, 1 and 3 μg showed an anticonflict effect which...
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