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Although the immunomodulatory properties of ursodeoxycholic acid (UDCA) have been well documented, the effects of UDCA on mast cell function are unknown. The aim of the present study was to investigate in vitro the effects of UDCA on histamine release from mast cells induced by a hydrophobic bile acid (i.e. chenodeoxycholic acid) and by classical mast cell activators (i.e. compound 48 and concanavalin...
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