The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Objective
To investigate the role of interleukin‐23 (IL‐23) in pathologic bone remodeling in inflammatory arthritis.
Methods
In this study we investigated the role of IL‐23 in osteoclast differentiation and activation using in vivo gene transfer techniques in wild‐type and myeloid DNAX‐activation protein 12–associating lectin‐1 (MDL‐1)–deficient mice, and by performing in vitro and in vivo osteoclastogenesis...