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A novel renewable immunosensor was created comprising a temperature-controlled surface composed of poly(n-isopropylacrylamide) (PNIPAAm)–antibody conjugates that could reversibly bind the antigen. Bovine serum albumin (BSA) and the corresponding antibody (anti-BSA) were chosen as a model antibody–antigen system to demonstrate the concept. The thermally responsive PNIPAAm conjugated to anti-BSA displayed...
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